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Informatie voor zorgverleners Behandelprotocollen Transfusieprotocol Transfusieprotocol hemato-oncologie Richtlijnen en literatuur

Richtlijnen

Behoudens de CBO richtlijn is er op dit moment geen specifieke richtlijn voor transfusie­beleid bij hemato-oncologische patiënten.

Klik HIER voor het consensusvoorstel Bloedtransfusiebeleid rondom stamcel­trans­plantaties (2024) van de Nederlandse SCT centra en Sanquin.

Literatuur

  1. Bergamin et al. Liberal versus restrictive transfusion strategy in critically ill oncologic patients: the transfusion requirements in critically ill oncologic patients randomized controlled trial. Crit Care Med 2017; 45(5):766-773
  2. DeZern et al. RBC transfusion triggers in acute leukemia, a randomized pilot study, Transfusion 2016; 56(7)-1705-1757
  3. Docherty et al. Effect of restrictive versus liberal transfusion strategies on outcomes in  patients with cardiovascular disease in a non-cardiac surgery setting: systematic review and meta-analysis. British Medical Journal 2016 Mar29; 352:i1351
  4. Estcourt et al. Restrictive versus liberal red blood cell transfusion strategies for people with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stemcell support. Cochrane Database Syst Rev. 2017; 1(1):CD011305
  5. Goerge et al. Inflammation induces hemorrhage in thrombocytopenia. Blood 2008; 111(10):4958-64
  6. Lars, Holst et al. Lower vs higher hemoglobin threshold for transfusion in septic shock (TRISS trial). N Engl. J Med 2014; 371:1381-1391
  7. Rygard et al. Higher vs. lower haemoglobin threshold for transfusion in septic shock: subgroup analyses of the TRISS trial. Acta Anaesth Scand. 2017; 61(2):166-175
  8. Cumpelik et al. Mechanism of platelet activation and hypercoagulability by antithymocyte globulins (ATG). Am. J. Transplant 2015; 10:2588-2601
  9. Langer et al. Mechanisms of platelet activation by antithymocyte globulin (ATG). Blood 2006; 108(11):3905
  10. Scheinberg et al. Horse versus rabbit antithymocyte globuline in acquired aplastic anemia. N Engl J Med 2011; 365:430-438
  11. Netelenbos et al. Transfusieadviezen na transplantatie: behoefte aan meer eenduidigheid in de CBO-richtlijn. Ned Tijdschr Hematol 2014; 11:64-71
  12. Bosch et al. Safety and efficacy of a Hb-triggered single-unit red cell transfusion policy for haemato-oncological inpatients. Br J Haematol 2021; 195(4):154-156
  13. Carson et al. Restrictive or liberal transfusion strategy in myocardial infarction and anemia. N Engl J Med 2023; 389(26):2446-2456 
  14. Carson et al. Transfusion thresholds and other strategies for guiding red blood cell transfusion (review). Cochrane Database Syst Rev 2025; 10(10):CD002042 
  15. Ducrocq et al. Effect of a restrictive vs liberal blood transfusion strategy on major cardiovascular events among patients with acute myocardial infarction and anemia: the REALITY randomized clinical trial. JAMA 2021; 325(6):552-560
  16. Mazer et al. Restrictive or liberal red-cell transfusion for cardiac surgery. N Engl J Med 2017; 377(22):2133-2144
  17. Murphy et al. Liberal or restrictive transfusion after cardiac surgery. N Engl J Med 2015; 372(11):997-1008

 

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